Central Nepal is dominated by Annapurna Himal and the town of Pokhara. There are three major trekking routes in this region; to Jomsom, to Annapurna sanctuary and a circuit of the entire Annapurna massif. Pokhara is also a good starting place for number of shorter treks around Annapurna region.

The ancient kingdom of Lo ( Mustang) is also geographically a part of the Annapurna region, but because treks to Mustang are subject to especial restriction.
About two-third of the 100,000 trekkers who visited Nepal in 2003/2004 trekked in the Annapurna region. The area is easily accessible, hotels in hills are plentiful and treks here offer good scenery of both high mountains and lowland villages.